Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

I used to go fishing in Vancouver with my dad until just a few years ago we found the fish full of cancers. And now we hear about animals and plants going extinct every day -- vanishing forever. 以前和我爸爸经常在vancouver钓鱼,但在近几年却发现鱼的身上到处是癌细胞。我们每天都会听说有的动物和植物绝种,那是永远消失的事情。
支出提升三成是由更专业的创新药品,更多患者支付得起药品以及放宽专利期限这些因素驱动的。
'In the meantime, the U.S. continues to grow its own domestic production both in oil and gas. I think, for us, it's less about where the actual price is going--it's more about how much more growth is left in North American oil sands, shale gas, shale oil,' as well as shale exploration elsewhere, he said.
2.《洛奇》
英国《金融时报》2017年高管教育排行榜列出了全球85个最佳定制课程和75个最佳开放课程。排名主要基于学员和客户的满意度以及学校收入增长、国际化程度和师资多样性等指标。
所有人身上都存在着这两种认同,但是人们倾向于更认可他们“最好”的身份——也就是能带给他们最高社会地位或特权的认同。举例来说,事业有成的职业人士通常以事业生涯来定义自己的身份。
Actor in a Mini-Series or Movie: Courtney B. Vance, “The People v. O. J. Simpson: American Crime Story”
在1981年,全球52%的人极其穷困潦倒。这个数字在2010年的时候下降了21%,少于7.21亿人还过着极度贫困的生活。
城镇新增就业1100万人以上,城镇登记失业率4.5%以内;
Nova School of Business and Economics consolidated last year’s strong performance by climbing a further 14 places to 17.
The prospect of a major shakeup right before the deadline is usually a recipe for disaster, especially if it leads to immediate roster change.
单词statement 联想记忆:
The first chart shows the total incidence of banking, currency and debt default crises in emerging markets since the 1970s, set against the nominal federal funds rate. Mr Koepke gives this as evidence that high and rising rates typically precede periods of EM crisis.
"Some geniuses in the internet industry created miracles, but that does not tell the whole story," said Chen. "Business has its own rules. Before you start up, you have to know how to produce products, how to sell them, how to manage a company. Those lessons you cannot expect a fresh graduate to know."
At the start of the year, the ruling Communist party set a target of 6 per cent growth in trade for this year but total trade has now fallen by just over 8 per cent in the first ten months of 2015 compared with the same period a year earlier.
确实,现在的保罗更大更强壮了,但是,现在的他脸蛋和高中的自己一样。在高中的时候,保罗甚至就有了自己标记性的胡须。
影片由斯蒂芬?斯皮尔伯格执导,梅丽尔?斯特里普和汤姆?汉克斯主演,讲述了一次激动人心的合作。凯瑟琳?格雷厄姆(斯特里普饰)是美国第一位大型报刊女性出版商,故事里,她与编辑本?布拉德利(汉克斯)力争抢先于《纽约时报》大规模报道美国政府的秘密。这些秘密尘封了三年,涉及四位总统。他们把自己的事业前途——以及人身自由——都赌在了这一次冒险上,双方必须合作,解决彼此之间的不和,才能携手将真相披露在大众面前。
[?'p?uzd]
and the regime's first move—cashing in Lou Williams to the Rockets for a first-round pick—is a clear sign they realize that they must do everything to retain their own top-three protected pick in June's draft.
The import side of the equation fared worse in both renminbi- and dollar-terms.
But if the U.S. can avert that Washington-made crisis, the outlook for workers finding jobs is actually looking pretty good for next year. For one thing, the damage of superstorm Sandy will have to be repaired, meaning jobs in construction and retail. Businesses, meanwhile, which have held off investing and hiring because of uncertainty over the fiscal outlook, might finally open their wallets. That means more jobs, too.[qh]
The index fell from 50.4 in October to a six-month low of 50.0.
10.专注工作,调节平衡
截至2016年底,中国仍有4300万农村地区的人口生活在贫困状态下。中国的目标是在2020年时帮助他们脱贫。
A cheery New Year hold lots of happiness for you!给你特别的祝福,愿新年带给你无边的幸福、如意。


愿明亮喜庆的新年烛光温暖一年中的每个日日夜夜,祝你欢欢喜喜度新年!
Online sales contributed 82.6 percent of sales. Online sales have prompted traditional stores, including 13 of Beijing's 77 "time-honored brands" from snack stores to shoes sellers, to move their goods online.
凯特·温丝莱特凭借她在电影《乔布斯》中扮演的乔安娜·霍夫曼一角斩获金球奖最佳女配角奖项。当她听到自己获奖时,她目瞪口呆地坐在椅子上不敢相信。


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

单词extend 联想记忆:
Johan Pettersson被授予搞笑化学奖,以表彰其揭示了瑞典小城Andersl?v居民的头发会变绿的原因,因为这里的水中含铜量太大。
《速度与激情6》帮助其另外两位男演员在我们榜单中获得较高的排名:范·迪塞尔(Vin Diesel)和已故的保罗·沃克(Paul Walker)。迪塞尔以8.87亿美元位居我们榜单第四。《速度与激情6》在全球斩获7.89亿美元的票房。仅仅几个月之前,他出演的《星际传奇3》(Riddick)在各大影院上映,仅收入9,800万美元票房,不过,这也足以使迪塞尔的排名领先于他的搭档沃克。
Hurricane Irma

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

Two weeks later, Mr. Bernheimer was among the dozens of long-established old master dealers attending the London evening sales. In the past, they would buy at these auctions to stock up for the Maastricht European Fine Art Fair in March in the Netherlands. But with sellers encouraging Sotheby’s and Christie’s to compete for their business with ever-higher valuations, and auctions now marketed to a shallow pool of wealthy buyers, there was conspicuously little trade bidding.

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

Are you heading to Rio for the Olympics? Will you leverage the Google Maps app on Android or iOS? I think you already have the answer.
第一种看法是,油价本质上具有周期性。下跌之后必然会回升。这道波谷越深,下一个山峰就越高。

Writing for a Comedy Series: Aziz Ansari and Alan Yang, “Master of None” (“Parents”)
In 2008, Janah talked to a call center worker from Dharavi, India, the largest slum in South Asia, while working as a consultant. The worker said there were millions of unemployed villagers as talented as he was. "I thought, 'What if outsourcing could generate a few dollars for billions of people, rather than billions of dollars for a wealthy few'" Janah says. She went on to launch Samasource, a tech platform that connects impoverished women and youth with large corporations like Google, LinkedIn, and Microsoft to complete digital projects. To date, the non-profit has helped over 16,000 people rise above the poverty line and it recently launched SamaUSA, a domestic program for low-income students living in San Francisco.
昔日影坛风光无限米高梅公司重组计划已获得批准,电影公司将由望远镜娱乐公司( Spyglass Entertainment )掌舵再次出发。而MGM也将不会在作为电影电影发行公司,而仅仅是一个制作公司。这使得第二十三部《007詹姆斯-邦德》电影问世日期更加具体化。
Profits at China’s biggest banks shrank in 2015, as the sector weathered a year of central bank rate cuts and saw an end to easy profits after the government lifted the cap on interest rates on deposits.
我们不希望看到打贸易战,贸易战带不来贸易公平,而且双方都受损。
10月份,日本生产增长速度突然提升,让决策者对日本经济的实力有了更多希望,或许也可以理解为释放了更多喜忧参半的信号。

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


南国置业4日发生1笔大宗交易 成交4612.88万元


References

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2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


为期三天的"中国发展高层论坛2016"近日在北京开幕。
“LBS has a great student body, very diverse in terms of nationality, competitive and intelligent,” commented one American graduate from the class of 2012. “It also gave me the opportunity to study in the US [on exchange] without having to do a purely US-focused American MBA.”
这篇文章指出,食用有益于心脏的食物是防止痴呆、保护记忆力的关键。一些心脏病的并发症和阿尔茨海默症以及痴呆症的并发症十分相似,因此研究阿尔茨海默症和痴呆症的教授们认为,有益于心脏的食物大概也有益于大脑和记忆。水果、蔬菜、全麦面包、豆子、坚果和橄榄油都有对心脏有益。如果这10个方法你不能都采用的话,一个健康的饮食至少能让你不要丢失记性。
adj. 人口统计学的
时间:2009-11-11 编辑:vicki
一份产业报告显示,随着国内手机制造商加快创新,国产品牌手机仍占据国内手机出货量的主要份额。
无论是过去还是现在,都有一系列通过煽动攥取权力的例子。
It’s sometimes one of the scariest words in the English language, but it’s a word you should be prepared to say when opportunities arise in your career: Yes.
想要谋杀老板的念头并不稀奇,但是当大家所讨论的老板真的死于谋杀时,就不是那么回事了。当警察来询问的时候,他们才知道,克兰斯顿兄弟俩已经辞职并骑着他们的摩托车横跨整个国家。他们俩在被证明清白之前都是嫌疑人。
Even if Gibson turns out to be a rental and leaves as a free agent this summer, the Thunder will likely feel good about these trade terms.

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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The ICMJE is small group of editors of general medical journals who first met informally in Vancouver, British Columbia, in 1978 to establish guidelines for the format of manuscripts submitted to their journals. The group became known as the Vancouver Group. Its requirements for manuscripts, including formats for bibliographic references developed by the U.S. National Library of Medicine (NLM), were first published in 1979. The Vancouver Group expanded and evolved into the International Committee of Medical Journal Editors (ICMJE), which meets annually. The ICMJE created the China has broken into the world's top 25 innovative economies for the first time, thanks to investments in education and research and development that have translated into new patents and licenses, a study said on Monday. to help authors and editors create and distribute accurate, clear, easily accessible reports of biomedical studies.

“…was caught in a big lie on her resume during the meeting.”
单词effective 联想记忆:
达洛伊西奥也尽力维持着生活原本的样子。他的女友还是之前的那个女友。而且尽管他不再去学校了──坐在教室里就没空监管Summly的研发──他还是照常去找老师拿作业。他十分庆幸他的朋友不了解他企业家的那一面。而当我采访他的时候,他正准备和一群高中死党去希腊玩上一周。
中国的网红经济发展到今天,经历了三个阶段:第一个阶段是文字时代,第二个阶段是图文时代,现在这一阶段是要归功于宽带的可用性的视频时代。

该银行预测,寻找对冲通胀的方式的指数基金(那些追踪大宗商品指数的基金),将在明年下半年回归农产品市场。

  • Only the first three authors are listed, followed by "et al."
  • 商改住被指违规成本低:开发商最多被罚几万元
  • 地产中介责任不可推卸 监管加码加速洗牌


流行音乐界永远的一号叛逆者夏洛特·艾玛·艾奇逊带着一张出色又令人惊讶的混合专辑回归了。
排放量去年的增幅比过去十年中2.5%的平均增长率略低,而且排放量增幅之所以下降,很大程度上是由中国经济增长放缓所引起的。中国是世界上最大的温室气体排放国。可能还需要再花一到两年时间,才能弄清楚中国排放量的增长究竟有没有放缓,还是最近数年那种极高的增速仍会持续。

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